Our Vision

Our vision is to improve patient care using integrated approaches involving laboratory models, mathematical models and machine-learning/Al methods to reduce time to bringing new therapies to market and to optimize treatments for patients after regulatory approval.

Our tools include quantitative wet laboratory models made of human-tissue, non-linear dynamical systems, and non-linear mathematical models, which we wrote from scratch and coded, for drug discovery development.

Our physician dominated team uses clinical and pathophysiologic know-how, the mathematics of topology and morphism mapping and category theory, to map disease response from the preclinical models to patients, so that readouts in our preclinical models will give precise rates of responses expected in patients, not just in terms of how many patients respond to therapy, but how fast, and the optimal duration of such therapy, and the doses to minimize failure and resistance to therapy. Thus, we can forecast clinical responses in early preclinical development, and then design adaptive clinical trials de novo, including the biomarkers of therapeutic response, duration of therapy, thereby de-risking time (decades), money (millions), and clinical trial patients’ lives (unquantifiable).

We also design combination therapy regimens using factorial design to find best companion drugs and doses for therapeutics.

Our motto summarizes it all. Quantify. Predict. Cure.

Meet Our Leadership Team

Tawanda Gumbo, M.D.
President & CEO, Founder

 

David Howe, PhD.
Vice President & CSO / COO

 

Meet Our Scientific Team

Shruti Athale, PhD.

 

Claude Bernal

 

Moti Chapagain, M.D., PhD.

 

Alma Gallardo

 

Tawanda Gumbo, M.D.

 

David Howe, PhD.

 

Thearith Koeuth

 

Jotam Pasipanodya, M.D., DrPH

 

Swati Patel, M.S. Biotechnology

 

Praedicare Africa Team

 

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Our Departments

Quality Control & Quality Assurance

Pharmaceutical Chemistry, Manufacturing & Controls

Molecular Biology & Technology Development Lab

Hollow Fiber System & Experimental Therapeutics Labs

Quantitative Preclinical & Clinical Sciences

Clinical Trials: FIH, Phase I-IV

Data Protection Security

Business Development & Partnerships

Business Manager

Interested in learning more?

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